The Argonaute (Ago) enzyme complex plays a critical role in DNA and RNA target cleavage for a process known as RNA silencing in prokaryotic and eukaryotic cells, making them a target for future ...

The origins of complex, nucleated cellular life – everything from amoebas to humans – may date back a lot further in Earth's ...

What makes distinct species have different proteins? Is there a key that allows eukaryotic cells to produce proteins involved in multicellularity that are mostly absent in prokaryotes? What makes ...

Prokaryotes are ancient, simple forms of life that include bacteria and archaea. These cellular life forms lack membrane-bound organelles. Those organelles, which include the nucleus and the ...

A lot happened in the hundreds of millions years separating the first and last eukaryotic common ancestors, but when and how most features arose remains a mystery. Eukaryogenesis is broadly defined as ...

The CRISPR technology commonly used for genome editing was originally based on bacterial defense mechanisms that arose to protect against bacteriophages, though their mode of activation has largely ...

Enzymes have clearly defined active sites to allow the substrate molecule to fit intricately. This is often coupled with an enzymatic conformational change prior to the occurrence of the catalysis ...